The son of John W. Powers (1784- ) and Susannah Sheppard (1784- ) of Goochland, Virginia. Jack's parents likely lived in Goochland county at the time of his birth, according to tax censuses but no birth record has been found. The Powers elders moved west, to lands beyond the Ohio river, about 1820-27. Jack eventually moved to Dubois county, IN where he married, made his house and farm.

Husband of Elizabeth 'Bettie' Shirley (1784-1876) of Adair county, KY, a daughter of William H. Shirley (1789-1845) and Nancy B. (Froman) Shirley (1797-1860) findagrave memorial #117767999). Jack and Bettie were married on January 6, 1839 in Dubois County, Indiana

Children of Jack and Bettie:
Infant P. Powers (ca.1855 - 1855) Died as an infant.
William John Powers (1841 - 1917)
John Thomas Powers (1843 - 1921)
Nancy Jane Powers Grigsby (1845 - 1913)
Mary Susan Powers Smith (1848 - 1903)
Joanna Frances Powers Morrison (1851- 1939)
Lucy Nae Powers Tucker (1853 - 1910)
Elizabeth Rush Powers Graham (1859 - 1930)

Siblings:
Mahala Lois Powers Appleberry (1827 - 1919)
William J. Powers (1831 - 1926)

Census data:
November 7, 1850 at Carroll County, Missouri
Home of (Father) John W Powers, age 66 and wife (mother) Susan, age 63, both born in Virginia, and their children William J, age 19 and (his wife) Sarah (nee Shirley), age 20, both born in Indiana.
Next door is the home of their son John (Jack) A. Powers, age 34, born in VA, his wife Elizabeth (Bettie), age 24, born in Indiana, and their children, William, 9, John, 7, Nancy J, 5, Susan, 2 and Frances, 2m (aka Joana).
Nancy (nee Froman) Shirley, 56, of KY, and her son Isaac, 17, of IN, also live here. (Nancy is the mother of Elizabeth and Sarah)

On the 1860 census at Morris Township, Carroll, Missouri, USA, John A Powers and family are seen living with his elderly parents John W & Susan Powers.
July 13, 1870 at Carroll County, Missouri
John L Powers M 54 Virginia
Elisabeth Powers F 49 Indiana
Joana Powers F 19 Missouri
Lucy A Powers F 16 Missouri
Elisabeth R Powers F 13 Missouri

After the death of Elizabeth, John Anderson Powers married Eliza Jane (Winn) Rose (memorial #150934603) the widow of Vinson D. Rose. They were married in Carroll County on 4 December 1876 and had no children.

June 23, 1880 at Morris Twp, Carroll County, Missouri
J. A. "Pouers", age 64, b VA, and his second wife Eliza J, age 55, b NC, and Eliza's three children Caleb, Jefferson and Archibald Rose

From Bonnie Shirley Amery:[
This day, November 14, 2018, is a red-letter day for me.
In a conversation about ancestors with Judy Rose (Mrs. Stewart Rose),
I learned what newly wed, Judy Rose, had overhead the "Old Timers" discussing.
The Rose Family members were discussing the burial wishes of Eliza (Winn) Rose-Anderson. They were clear in the understanding that Eliza wanted to be buried beside her first husband and child. They also were very clear about the burial wishes of Eliza's second husband, John Anderson Powers. He wanted to be buried beside his first wife.

November 11, 2019, received a wonderful email from findagrave contributor, John Gavin,Fl, with the following new information: "This is evidence that Jack is descended from the same Powers family as my Major Powers. It is likely that Lewis Powers is Jack's grandfather and Lewis is probably the cousin of my ancestor. Major Powers. (who also had a son named John W Powers)."

The following tree page can help you see where they all fit into the Powers family of Virginia:
https://www.familysearch.org/tree/person/details/9CS1-J29